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If the whole bone marrow is removed in an ablative treatment (rather than a partial fashion), some of the clinical risks of the treatment remain. The big two risks with bone marrow transplants are 1) rejection of the new marrow and 2) infection, as the immune system is suppressed while the marrow regrows. Using one's own marrow with largely one's own DNA should (?) eliminate the first to a large degree, but the second still remains.