It's an interesting idea. But I think it shares the same design flaw as C# and Java: it's designed for people dumber than its creator. He says it himself:

I probably couldn't use this for work

I think the best products are designed for their creators' own use, or at least for people perceived as intelligent as the designer.

There's definitely a line somewhere. I mean, the average user isn't going to use emacs or vim. But I think this is way past that line.

For example, I'm pretty strongly on the "minimal settings" side of design. But some settings are necessary. Sometimes you really do have relevant percentages of users who want different things. I think his "no settings" idea just isn't feasible.

I don't know, maybe his starting point of "segmented browsers" is a better approach.

Malcolm Gladwell has a TED talk where he basically says the brand with the most choice wins. Because there is no "perfect" spaghetti sauce. People are different. But if you have a dozen flavors, you'll get 12 markets instead of 1.

Maybe browsers should take the same approach?