This guy. You win again. @redsox44344, this really is the only answer. You put in the time for your degree and now is the time to make it work for you. Even if this opportunity doesn't come close to the top of your most desired jobs list, you will be making real money and have real benefits. Like @kleinbl00 said, the best time to find another job is when you already have one. Stepping stones, etc. That said, it sounds like you're dealing with burnout more than anything else. Good news there too: more than likely you just need a real change of pace, and more than likely, that is exactly what you will get upon entering the commercial sector. Take the plunge. If it doesn't work, I'm fairly confident in your ability to submit resumes elsewhere..