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The hope is that we can modify the exosomes so they have anti-tumor effects the go beyond the RNAs that we introduce to the producer cells that can be packaged in the exosomes they then export. It looks like the native cargo of marrow stromal exosomes can be supportive or suppressive based on the environment of the MSCs when they produce them. That is, they contain a cargo profile that has an effect upon tumor, and we want to bias that profile. Re: Weinberg. That's awesome. Should get an autograph. :)