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If there's anywhere that bias needs to be reduced, it's in the grant awarding process. I'm not entirely sure how big a deal it is in publishing. I'm sure it exists, but eventually, if your paper is good, it's going to get out there, even if it's not in the top impact journals. In this day and age, what's the difference. As long as I can read an article and judge it on my own, I could not possibly care less who publishes it. Remember, the Lancet is the journal that published that rubbish about vaccines and autism. Meanwhile, plenty of high quality research is published in journals whose impact factor is ~2. The grants thing is way easier said than done.