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To me there are some things that can't be chalked up to cultural differences, and I don't hesitate to call them barbaric. Most of these things satisfy these criteria: tradition, torture, myth and misogyny. In addition to FGM, so called honor killings satisfy these criteria, as does the rape that is endemic to parts of sub-Saharan Africa. I'm sure there are a lot of others that I could brainstorm.
In the West we have the underground sex trade. That fails the religious criteria, so while it is equally disgusting, I think it is more of a law enforcement issue. No one in the main stream would argue against efforts to shut it down.