I think a lot of people would benefit from the shift in perspective this comic gives. ...but... I've felt joy. I've felt bliss. But those feelings are ephemeral. Being "happy" implies permanence I don't agree with his premise that happiness is permanent and unchanging though. Why would it be? I think he's using happiness as a blunt euphemism for "a successful station in life" where we're given never ending short term goals to be measured against some kind of material criteria (test scores, grades, a job, a promotion, a boy/girlfriend, earnings, a car, a house....,) rather than an internal sense of well being (yeah and now I'm being obtuse and vague.) These things are ridiculously difficult to describe - "like catching water with a net". I'm eternally grateful I learned meditation in my mid 20s because that gave me an alternative perspective earlier than I think I would have found without it. That's part of what this comic is alluding to (reading a bit between the lines) as well as the idea of "flow" or being absorbed timelessly in your current activity. But I've never felt "happy".