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It's a good cartoon, but I actually think it overcomplicates the issues. They hit the nail on the head in one single panel, which is having to prove that you prespecified what your analysis would be before you did any measurements. That's the only way to ensure that your a priori odds match with your statistical analysis. I also think that publishing per se is less of an issue than grant funding. If every scientist weren't on the hook to pay his/her own salary via federally funded grants, that immense pressure wouldn't exist. There's no university in America who gives a fuck what your publication rate is if you're bringing in a million per year.