"You're fed up with him, but I have to deal with him even more often than you," Obama replied.
Pretty good stuff. Considering how much of a thorn Netanyahu has been in Obama's side, I'm surprised his response was so measured.
Of course, the GOP will try to use this to weaken Obama. However, I think that there is a ever-growing contingent of the US that is skeptical of unilateral US support for Israel, on both sides of the political spectrum. IMHO Netanyahu's behavior towards the US has decreased the value that might be seen in the relationship. I think this might actually look good for Obama.