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Too many unknowns in general. We'll be teasing out the details for decades after legalization. I'll probably start reading meta-studies sometime around 2050. Of course, that's if I can still read by then, after all the pot I plan to smoke* in the meantime. So far, I'm the best lab rat for me. Haven't been able to conduct any double-blind studies with myself (still working on developing that schizophrenia), but single-blind studies are going well. I can distinguish between many jelly bean flavors, and between several mainstream psychedelics. *I've gotta get a vaporizer...