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Comments are not weighted on Karma by reddit, but recognizable names are immediately upvoted or downvoted regardless of posts. See WarPhalange for a downvote magnet, or pretty much any other power user for a massive upvote magnet.
The effect is less than you might imagine, particularly now. Over the past year I've gone from being "oh, of course you're being upvoted, you're kleinbl00" to "why are all these people downvoting you?" I know where the bodies are buried and WarPhalange isn't even on my radar. I'd say less than 1% of Reddit's users these days could name five users.