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I've always found futura book very enjoyable to read. I've goofed around with serif fonts here, and it never makes easier to read. However, ink and screen are not the same. IMO nytimes isn't any less readable in helvetica, but it does seem to lose some gravitas:
The fonts that have always seemed the easiest and least resistant to my eye are most often sans. There are certain serifs that are easier to read than certain sans, but on the balance I find sans more amenable I think. Print is where I like to see serifs though.